[01] Sboui Amel, Livestock and Wildlife Laboratory, Arid Land Institute, Medenine, Tunisia. [02] Agrebi Aroua, Veterinary School, Laboratory of Physiology and Therapeutic, Sidi Thabet, Tunisia. [03] Belhadj Omrane, College of Science, Biochemistry and Technobiology Laboratory, Tunis, Tunisia. [04] Khorchani Touhami, Livestock and Wildlife Laboratory, Arid Land Institute, Medenine, Tunisia.

This research was conducted to follow our previous research to evaluate the antidiabetic effect of coagulum from camel milk in alloxan diabetic dogs. Diabetes was induced by intravenous injection of alloxan (65 mg/kg bodyweight). The effects of camel milk on diabetic dogs were investigated by observing changes in the glycometabolic index (fasting blood glucose, IGTT test), the lipometabolic index (triglyceride, cholesterol), and total proteins and in the degree of injury of β-cells in the pancreatic islets. Diabetic dogs were divided into 2 groups getting respectively the coagulum obtained from 250 ml of camel milk and the whey gotten from the same quality of milk. For the group treated with coagulum from camel milk; a significant decrease in fasting plasma glucose (from 10 ± 1.02 mmol/l to 6.2 ± 0.48 mmol/l), cholesterol (from 7.46 ± 1.48 mmol/l to 4.76 ± 1.1 mmol/l) and total proteins (from 84.16 ± 7.18 g/l to 64.2 ± 7.41g/l) in blood sample and an improvement on the animal clinical state (increase of body weight, normal activity) were revealed. Treatment with coagulum from camel milk also induces the renewal of pancreatic b-cells. Treatment with whey from camel milk doesn’t have any benefit effect on diabetic dogs. The curative effect of camel milk on diabetic dogs was approved in this study. This effect was observed using coagulum from camel milk as treatment.

Coagulum, Camel Milk, Diabetes

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