Clinical Medicine Journal
Articles Information
Clinical Medicine Journal, Vol.4, No.4, Dec. 2018, Pub. Date: Dec. 21, 2018
Photodynamic Therapy for Treatment of Subfoveal Choroidal Neovascularization in Exudative Age-Related Macular Degeneration
Pages: 60-66 Views: 1493 Downloads: 299
Authors
[01] Burcu Dirim, Department of Ophthalmology, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey.
[02] Selam Yekta Sendul, Department of Ophthalmology, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey.
[03] Semra Tiryaki Demir, Department of Ophthalmology, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey.
[04] Ali Olgun, Department of Ophthalmology, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey.
[05] Dilek Guven, Department of Ophthalmology, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey.
Abstract
This retrospective study is designed to examine the results of photodynamic therapy (PDT) in our cases and compare our results with those of the previous studies. The data was collected from the files of 36 patients on whom PDT had been performed in the Retina Unit of the Ophthalmology Clinic of our Hospital. In the study group, gender, age, baseline best corrected visual acuity (BCVA), lesion types, mean PDT numbers, number of cases on whom multiple PDT were performed, mean visual acuity (VA) difference and the number of cases in the VA change groups were evaluated. The results were compared in themselves and with other studies. Although statistically not significant, predominantly classic and occult lesions responded to PDT better than the other one. After the estimation of all cases, a statistically significant increase was found between baseline and final VA results. Also in cases with low baseline BCVA, the benefit from the treatment was more significant than the other group. As a result of this study, it has been concluded that PDT with Verteporfin is an effective and reliable treatment that preserves visual acuity in CNV secondary to AMD. Further, for decreasing the frequency of PDT, combined therapies are also commonly preferred at present.
Keywords
Age-Related Macular Degeneration, Photodynamic Therapy, Verteporfin, Choroidal Neovascularization, Visual Acuity
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