[01] Upasana V. Patel, Ganga Ram Hospital, New Delhi, India. [02] Ish Anand, Ganga Ram Hospital, New Delhi, India. [03] Anuradha Batra, Ganga Ram Hospital, New Delhi, India.

Optic neuritis as a complication of varicella infection is rarely encountered. We hereby report a case of a 3-year-old immunocompetent boy who presented with sudden bilateral vision loss with recurrent generalised seizures and myoclonus four weeks after eruption of lesions of chickenpox. Ophthalmologic examination revealed only light perception in both the eyes with normal fundus examination, but prolonged latency in both eyes on visual-evoked potential (VEP), suggestive of bilateral retrobulbar optic neuritis. Preceding clinical history of chickenpox, findings of VEP and concomitant neurological involvement supported the diagnosis of post-varicella retrobulbar optic neuritis. After receiving a short course of intravenous methylprednisolone followed by tapering dose of oral steroid along with anti-epileptics, the visual acuity normalised bilaterally six months later.

Acyclovir, Chickenpox, Encephalitis, Optic Neuritis

[01] PurrinV, Hrisomallos M, Vandrik B, et al. Varicella optic neuritis. Neurology 1988; 38:501-3. [02] Galbussera A, Tagliabue E, Frigo M, et al. Isolated bilateral anterior optic neuritis following chickenpox in an immunocompetent adult. NeurolSci 2006; 27: 278-80. [03] Tappeiner C, Aebi C, Garweg JG. Retinitis and optic neuritis in a child with chickenpox. Pediatr Infect Dis. 2010; 29: 1150-1152. [04] Copenhaver RM. Chickenpox with retinopathy. Arch Ophthalmol. 1966; 75:199 –200. [05] Capone A, Meredith TA. Central visual loss caused by chickenpox retinitis in a 2-year-old child. Am J Ophthalmol. 1992; 113:592–593. [06] MacKinnon JR, Lim Joon T, Elder JE. Chickenpox neuroretinitis in a 9 year old child. Br J Ophthalmol. 2002; 86:475– 476. [07] SelbstRG. Parainfectious optic neuritis. Report and review following varicella. Arch Neurol. 1983; 40:347–350. [08] Roelandt V, Fayol L, Hugonenq C, et al. Retrobulbar optic neuritis and chicken pox: a case report in a child _in French_. Arch Pediatr. 2005; 12:278 –280. [09] Hatch H. Bilateral optic neuritis following chickenpox: report of a case with apparently complete recovery. J Pediatr. 1949; 34:758 –759. [10] Walsh F, Hoyt W. Clinical Neuro-ophthalmology. Baltimore, MD: Williams and Wilkins; 1969:1361–1369. [11] Bruguier A, Ponsot G, Khouri-Dagher L, et al. Neuromyelitisoptica or Devic disease complicating chickenpox (author’s transl) [in French]. Arch FrPediatr. 1981; 38:763–764. [12] Lee WH, Charles SJ. Acute retinal necrosis following chickenpox in a healthy 4 year old patient. Br J Ophthalmol. 2000; 84:667– 668. [13] Purvin V, Hrisomalos N, Dunn D. Varicella optic neuritis. Neurology. 1988; 38:501–503. [14] Underwood E. The neurological complications of varicella: a clinical and epidemiological study. Brit J Child Dis. 1935; 32:83–107, 177–196, 241–263. [15] StergiouPK, Konstantinou IM, Karagianni TN, et al. Optic neuritis caused by varicella infection in an immunocompetent child. Pediatr Neurol. 2007; 37:138 –139.