[01] Sham Yin Kee, Faculty of Medicine, Melaka-Manipal Medical College (Manipal Academy of Higher Education (MAHE)), Melaka, Malaysia. [02] Navvin Chelvam, Faculty of Medicine, Melaka-Manipal Medical College (Manipal Academy of Higher Education (MAHE)), Melaka, Malaysia. [03] Mohamad Affiq Azzuddin Bin Zaidi, Faculty of Medicine, Melaka-Manipal Medical College (Manipal Academy of Higher Education (MAHE)), Melaka, Malaysia. [04] Noorliyana Binti Kassim Selamat, Faculty of Medicine, Melaka-Manipal Medical College (Manipal Academy of Higher Education (MAHE)), Melaka, Malaysia. [05] Se To Ka Wai, Faculty of Medicine, Melaka-Manipal Medical College (Manipal Academy of Higher Education (MAHE)), Melaka, Malaysia.

Introduction: Young healthy adults are frequently exposed to the consumption of energy drinks and sports drink for various reasons. Energy drinks has higher tonicity and contains caffeine. Therefore, the objective of this study is to investigate the effect of energy drink and sports drink on cardiology parameters and alertness in comparison to mineral water among young healthy adults. Methodology: A randomized controlled trial was done in a private medical college in Malaysia from June 2018 to August 2018. Participants were divided into 3 intervention groups [hypertonic solution (n=37), isotonic solution (n=37), mineral water (n=37)]. They were given the intervention drink (250ml) and later given questionnaire (24 components) to assess alertness and record cardiology parameters (systolic and diastolic blood pressure, heart rate). The change in blood pressure and heart rate were analysed using ANOVA and independent T-test with Bonferroni adjustment. The adverse events of each intervention was analysed using Chi-square test and relative risk was calculated. Results: There was no significant differences among the three intervention groups except in hypertonic group there was significant difference in improvement of mental alertness, increase in systolic blood pressure and 5.5 times more likely to experience palpitation compared to mineral water group while mineral water group had significant difference in decreased heart rate. Conclusion: Hypertonic drink can improve the alertness but 29.7% of the participants experienced palpitation which was higher compared to other groups. However, there is no difference between mineral water and isotonic drink in terms of cardiology parameters and alertness.

Hypertonic, Isotonic, Mineral Water, Alertness, Cardiology Parameters

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