International Journal of Plant Science and Ecology
Articles Information
International Journal of Plant Science and Ecology, Vol.1, No.6, Dec. 2015, Pub. Date: Jan. 6, 2016
Phytochemical Screening and Biological Activities of Different Parts of Centaurea montana
Pages: 237-240 Views: 1391 Downloads: 1290
Authors
[01] Nisar Ahmad, epartment of Botany, Kohat University of Science and Technology, Kohat, Pakistan.
[02] Zabta Khan Shinwari, Department of Biotechnology, Quaid-i-Azam University, Islamabad, Pakistan.
[03] Javid Hussain, School of Biological Sciences and Chemistry, University of Nizwa, Sultanate of Oman.
[04] Ijaz Ahmad, Department of Chemistry, Kohat University of Science and Technology, Kohat, Pakistan.
[05] Razia Perveen, Department of Biotechnology, Kohat University of Science and Technology, Kohat, Pakistan.
[06] Salim Rehman, epartment of Botany, Kohat University of Science and Technology, Kohat, Pakistan.
Abstract
The crude extracts and its derived fractions {n-hexane, chloroform, ethyl acetate, n-butanol and residual aqueous fraction} of rhizome, leaves and flowers of medicinal plant Centaurea were subjected to microbicidy against Vibrio cholerae (ATTC9459), Salmonella typhe (ATTC700931), Acinitobacter baumanni (ATTC17978), Shigella dysenteriae (ATTC13313), Bacillus anthrax (ATTC14578), Moraxella lacunata (ATTC17967), Penicillium chrysogenum (ATTC28089), Candida albicans (ATTC2876), Aspergillus fumigatus (ATTC3626) and evaluation of chemical profile. The results revealed that n - hexane fraction obtained from rhizome of the plant showed outstanding (87.40% inhibition) antibacterial activity against Moraxella lacunata followed by crude extract of rhizome against Acinitobacter baumanni showing 82.50% inhibition. The crude extract and its derived fractions obtained from leaves of the plant showed moderate inhibition against all tested bacterial strains. The crude extracts/fractions obtained from the flowers of the plant were found inactive against all tested bacterial and fungal strains. Surprisingly none of the crude extracts/ fractions of the plant showed antifungal activity against the three tested fungal pathogens. Preliminary phytochemical screening of plant showed that rhizome and leaves are the rich source of fatty acids, flavonoids, alkaloids and glycoside.
Keywords
Medicinal Plants, Centaurea montana, Asteraceae, Antibacterial Activity, Antifungal Activity, Phytochemical Screening
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